April 2, 2022
East St. Louis - East St. Louis, IL
Girls' 4 x 800 Relay
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| PL | TEAM | ATHLETES | TIME | TIME | TIME | TIME | SC |
|---|---|---|---|---|---|---|---|
| 1 | Belleville East | Devynisha Deere, Bria Johnson, Brenae Falls, Tawney Anaya | 10:10.49 | 11:59.02 | 14:35.04 | 11:18.32 | 10 |
| 2 | East St. Louis | Di Najhia Griggs, Le'Nikei Burns, Brenay Smith, Zhakeya Hawkins | 8:45.35 | 11:33.17 | 14:13.69 | 12:09.65 | 8 |
| 3 | Hazelwood Central | Devyn Shelton, Aliya Catching, Skye Maxwell, Marsae Elam | 11:13.06 | 9:16.00 | 13:46.69 | 12:11.58 | 6 |
| 4 | Hazelwood East | Jocelyn Archie, Nevaeh Mosby, Chloe Rainey, Kendall Strong | 10:52.99 | 11:00.33 | 12:50.38 | 12:13.69 | 5 |
| 5 | Southeast (Springfield) | Melodi Victory, Jasiah Singleton, Mia Hinkle, Kairy Mercado | 9:32.42 | 12:38.07 | 16:45.61 | 12:53.54 | 4 |
| Lanphier | Ashley Watson, Sophie Lewis, Julia Longstaff, Mykail Brown | DNS | DNS | DNS | DNS |